Limited Correlation of Shotgun Metagenomics Following Host Depletion and Routine Diagnostics for Viruses and Bacteria in Low Concentrated Surrogate and Clinical Samples

The etiologic cause of encephalitis, meningitis or meningo-encephalitis is unknown in up to 70% of cases. Clinical shotgun metagenomics combined with host depletion is a promising technique to identify infectious etiologies of central nervous system (CNS) infections. We developed a straightforward e...

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Detalles Bibliográficos
Autores principales: Oechslin, Corinne P., Lenz, Nicole, Liechti, Nicole, Ryter, Sarah, Agyeman, Philipp, Bruggmann, Rémy, Leib, Stephen L., Beuret, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206298/
https://www.ncbi.nlm.nih.gov/pubmed/30406048
http://dx.doi.org/10.3389/fcimb.2018.00375

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