Cargando…
Selectivity Conversion of Protease Inhibitory Antibodies
Background: Proteases are one of the largest pharmaceutical targets for drug developments. Their dysregulations result in a wide variety of diseases. Because proteolytic networks usually consist of protease family members that share high structural and catalytic homology, distinguishing them using s...
Autores principales: | Lopez, Tyler, Ramirez, Aaron, Benitez, Chris, Mustafa, Zahid, Pham, Henry, Sanchez, Ramon, Ge, Xin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206439/ http://dx.doi.org/10.1093/abt/tby008 |
Ejemplares similares
-
Interlocus Gene Conversion, Natural Selection, and Paralog Homogenization
por: Yang, Yixuan, et al.
Publicado: (2023) -
Protease‐resistant streptavidin for interaction proteomics
por: Rafiee, Mahmoud‐Reza, et al.
Publicado: (2020) -
Selective antibody activation through protease-activated pro-antibodies that mask binding sites with inhibitory domains
por: Chen, I-Ju, et al.
Publicado: (2017) -
Bounding Bias Due to Selection
por: Smith, Louisa H., et al.
Publicado: (2019) -
Identification of HCV protease inhibitor resistance mutations by selection pressure-based method
por: Qiu, Ping, et al.
Publicado: (2009)