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Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria
A Panchgavya preparation was evaluated for its prophylactic efficacy against bacterial infection, employing the nematode worm Caenorhabditis elegans as a model host. Worms fed with the Panchgavya preparation prior to being challenged with pathogenic bacteria had a better survival rate against four o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206607/ https://www.ncbi.nlm.nih.gov/pubmed/30416718 http://dx.doi.org/10.12688/f1000research.16485.1 |
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author | Patel, Pooja Joshi, Chinmayi Funde, Snehal Palep, Hanumanthrao Kothari, Vijay |
author_facet | Patel, Pooja Joshi, Chinmayi Funde, Snehal Palep, Hanumanthrao Kothari, Vijay |
author_sort | Patel, Pooja |
collection | PubMed |
description | A Panchgavya preparation was evaluated for its prophylactic efficacy against bacterial infection, employing the nematode worm Caenorhabditis elegans as a model host. Worms fed with the Panchgavya preparation prior to being challenged with pathogenic bacteria had a better survival rate against four out of five test bacterial pathogens, as compared to the control worms. Panchgavya feeding prior to bacterial challenge was found to be most effective against Staphylococcus aureus, resulting in 27% (p=0.0001) better worm survival. To the best of our awareness, this is the first report demonstrating in vivo prophylactic efficacy of Panchgavya mixture against pathogenic bacteria. |
format | Online Article Text |
id | pubmed-6206607 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | F1000 Research Limited |
record_format | MEDLINE/PubMed |
spelling | pubmed-62066072018-11-09 Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria Patel, Pooja Joshi, Chinmayi Funde, Snehal Palep, Hanumanthrao Kothari, Vijay F1000Res Research Note A Panchgavya preparation was evaluated for its prophylactic efficacy against bacterial infection, employing the nematode worm Caenorhabditis elegans as a model host. Worms fed with the Panchgavya preparation prior to being challenged with pathogenic bacteria had a better survival rate against four out of five test bacterial pathogens, as compared to the control worms. Panchgavya feeding prior to bacterial challenge was found to be most effective against Staphylococcus aureus, resulting in 27% (p=0.0001) better worm survival. To the best of our awareness, this is the first report demonstrating in vivo prophylactic efficacy of Panchgavya mixture against pathogenic bacteria. F1000 Research Limited 2018-10-08 /pmc/articles/PMC6206607/ /pubmed/30416718 http://dx.doi.org/10.12688/f1000research.16485.1 Text en Copyright: © 2018 Patel P et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Note Patel, Pooja Joshi, Chinmayi Funde, Snehal Palep, Hanumanthrao Kothari, Vijay Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria |
title | Prophylactic potential of a
Panchgavya formulation against certain pathogenic bacteria |
title_full | Prophylactic potential of a
Panchgavya formulation against certain pathogenic bacteria |
title_fullStr | Prophylactic potential of a
Panchgavya formulation against certain pathogenic bacteria |
title_full_unstemmed | Prophylactic potential of a
Panchgavya formulation against certain pathogenic bacteria |
title_short | Prophylactic potential of a
Panchgavya formulation against certain pathogenic bacteria |
title_sort | prophylactic potential of a
panchgavya formulation against certain pathogenic bacteria |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206607/ https://www.ncbi.nlm.nih.gov/pubmed/30416718 http://dx.doi.org/10.12688/f1000research.16485.1 |
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