Cargando…

Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria

A Panchgavya preparation was evaluated for its prophylactic efficacy against bacterial infection, employing the nematode worm Caenorhabditis elegans as a model host. Worms fed with the Panchgavya preparation prior to being challenged with pathogenic bacteria had a better survival rate against four o...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Pooja, Joshi, Chinmayi, Funde, Snehal, Palep, Hanumanthrao, Kothari, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206607/
https://www.ncbi.nlm.nih.gov/pubmed/30416718
http://dx.doi.org/10.12688/f1000research.16485.1
_version_ 1783366380898222080
author Patel, Pooja
Joshi, Chinmayi
Funde, Snehal
Palep, Hanumanthrao
Kothari, Vijay
author_facet Patel, Pooja
Joshi, Chinmayi
Funde, Snehal
Palep, Hanumanthrao
Kothari, Vijay
author_sort Patel, Pooja
collection PubMed
description A Panchgavya preparation was evaluated for its prophylactic efficacy against bacterial infection, employing the nematode worm Caenorhabditis elegans as a model host. Worms fed with the Panchgavya preparation prior to being challenged with pathogenic bacteria had a better survival rate against four out of five test bacterial pathogens, as compared to the control worms. Panchgavya feeding prior to bacterial challenge was found to be most effective against Staphylococcus aureus, resulting in 27% (p=0.0001) better worm survival. To the best of our awareness, this is the first report demonstrating in vivo prophylactic efficacy of Panchgavya mixture against pathogenic bacteria.
format Online
Article
Text
id pubmed-6206607
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher F1000 Research Limited
record_format MEDLINE/PubMed
spelling pubmed-62066072018-11-09 Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria Patel, Pooja Joshi, Chinmayi Funde, Snehal Palep, Hanumanthrao Kothari, Vijay F1000Res Research Note A Panchgavya preparation was evaluated for its prophylactic efficacy against bacterial infection, employing the nematode worm Caenorhabditis elegans as a model host. Worms fed with the Panchgavya preparation prior to being challenged with pathogenic bacteria had a better survival rate against four out of five test bacterial pathogens, as compared to the control worms. Panchgavya feeding prior to bacterial challenge was found to be most effective against Staphylococcus aureus, resulting in 27% (p=0.0001) better worm survival. To the best of our awareness, this is the first report demonstrating in vivo prophylactic efficacy of Panchgavya mixture against pathogenic bacteria. F1000 Research Limited 2018-10-08 /pmc/articles/PMC6206607/ /pubmed/30416718 http://dx.doi.org/10.12688/f1000research.16485.1 Text en Copyright: © 2018 Patel P et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Note
Patel, Pooja
Joshi, Chinmayi
Funde, Snehal
Palep, Hanumanthrao
Kothari, Vijay
Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria
title Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria
title_full Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria
title_fullStr Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria
title_full_unstemmed Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria
title_short Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria
title_sort prophylactic potential of a panchgavya formulation against certain pathogenic bacteria
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206607/
https://www.ncbi.nlm.nih.gov/pubmed/30416718
http://dx.doi.org/10.12688/f1000research.16485.1
work_keys_str_mv AT patelpooja prophylacticpotentialofapanchgavyaformulationagainstcertainpathogenicbacteria
AT joshichinmayi prophylacticpotentialofapanchgavyaformulationagainstcertainpathogenicbacteria
AT fundesnehal prophylacticpotentialofapanchgavyaformulationagainstcertainpathogenicbacteria
AT palephanumanthrao prophylacticpotentialofapanchgavyaformulationagainstcertainpathogenicbacteria
AT kotharivijay prophylacticpotentialofapanchgavyaformulationagainstcertainpathogenicbacteria