The role of cell therapies and hip arthroscopy in the management of osteonecrosis: an update

The exact pathophysiology of osteonecrosis of the femoral head (ONFH) is still unknown. There is evidence to suggest that in ON there is decreased population and altered function of the mesenchymal stem cells (MSCs) of the femoral head. This could influence both the actual occurrence of ON itself an...

Descripción completa

Detalles Bibliográficos
Autores principales: Papavasiliou, Athanasios V, Triantafyllopoulos, Ioannis, Paxinos, Odysseas, Tsoukas, Dimitrios, Kostantoulakis, Charalambos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206693/
https://www.ncbi.nlm.nih.gov/pubmed/30393546
http://dx.doi.org/10.1093/jhps/hny021
_version_ 1783366400534904832
author Papavasiliou, Athanasios V
Triantafyllopoulos, Ioannis
Paxinos, Odysseas
Tsoukas, Dimitrios
Kostantoulakis, Charalambos
author_facet Papavasiliou, Athanasios V
Triantafyllopoulos, Ioannis
Paxinos, Odysseas
Tsoukas, Dimitrios
Kostantoulakis, Charalambos
author_sort Papavasiliou, Athanasios V
collection PubMed
description The exact pathophysiology of osteonecrosis of the femoral head (ONFH) is still unknown. There is evidence to suggest that in ON there is decreased population and altered function of the mesenchymal stem cells (MSCs) of the femoral head. This could influence both the actual occurrence of ON itself and the repair process that follows. Hence, in such an environment it only is rational to consider the use of cell-based treatments to potentially regenerate lost or damaged bone. The aim of this review is to provide an up-to-date, evidence-based information in the use of cell therapies in the treatment of nontraumatic ONFH and the use of hip arthroscopy in the field.
format Online
Article
Text
id pubmed-6206693
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-62066932018-11-02 The role of cell therapies and hip arthroscopy in the management of osteonecrosis: an update Papavasiliou, Athanasios V Triantafyllopoulos, Ioannis Paxinos, Odysseas Tsoukas, Dimitrios Kostantoulakis, Charalambos J Hip Preserv Surg Review Articles The exact pathophysiology of osteonecrosis of the femoral head (ONFH) is still unknown. There is evidence to suggest that in ON there is decreased population and altered function of the mesenchymal stem cells (MSCs) of the femoral head. This could influence both the actual occurrence of ON itself and the repair process that follows. Hence, in such an environment it only is rational to consider the use of cell-based treatments to potentially regenerate lost or damaged bone. The aim of this review is to provide an up-to-date, evidence-based information in the use of cell therapies in the treatment of nontraumatic ONFH and the use of hip arthroscopy in the field. Oxford University Press 2018-06-14 /pmc/articles/PMC6206693/ /pubmed/30393546 http://dx.doi.org/10.1093/jhps/hny021 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Review Articles
Papavasiliou, Athanasios V
Triantafyllopoulos, Ioannis
Paxinos, Odysseas
Tsoukas, Dimitrios
Kostantoulakis, Charalambos
The role of cell therapies and hip arthroscopy in the management of osteonecrosis: an update
title The role of cell therapies and hip arthroscopy in the management of osteonecrosis: an update
title_full The role of cell therapies and hip arthroscopy in the management of osteonecrosis: an update
title_fullStr The role of cell therapies and hip arthroscopy in the management of osteonecrosis: an update
title_full_unstemmed The role of cell therapies and hip arthroscopy in the management of osteonecrosis: an update
title_short The role of cell therapies and hip arthroscopy in the management of osteonecrosis: an update
title_sort role of cell therapies and hip arthroscopy in the management of osteonecrosis: an update
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206693/
https://www.ncbi.nlm.nih.gov/pubmed/30393546
http://dx.doi.org/10.1093/jhps/hny021
work_keys_str_mv AT papavasiliouathanasiosv theroleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate
AT triantafyllopoulosioannis theroleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate
AT paxinosodysseas theroleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate
AT tsoukasdimitrios theroleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate
AT kostantoulakischaralambos theroleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate
AT papavasiliouathanasiosv roleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate
AT triantafyllopoulosioannis roleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate
AT paxinosodysseas roleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate
AT tsoukasdimitrios roleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate
AT kostantoulakischaralambos roleofcelltherapiesandhiparthroscopyinthemanagementofosteonecrosisanupdate

Ejemplares similares