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Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma

Glioblastoma (GBM) is one of the most common, deadly, and difficult-to-treat adult brain tumors. Surgical removal of the tumor, followed by radiotherapy (RT) and temozolomide (TMZ) administration, is the current treatment modality, but this regimen only modestly improves overall patient survival. In...

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Detalles Bibliográficos
Autores principales: Harder, Bryan G., Blomquist, Mylan R., Wang, Junwen, Kim, Anthony J., Woodworth, Graeme F., Winkles, Jeffrey A., Loftus, Joseph C., Tran, Nhan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206841/
https://www.ncbi.nlm.nih.gov/pubmed/30406029
http://dx.doi.org/10.3389/fonc.2018.00462