Cargando…

Comparing diagnostic and prognostic performance of two-gene promoter methylation panels in tissue biopsies and urines of prostate cancer patients

BACKGROUND: Prostate cancer (PCa) is one of the most common cancers among men worldwide. Current screening methods for PCa display limited sensitivity and specificity, not stratifying for disease aggressiveness. Hence, development and validation of new molecular markers is needed. Aberrant gene prom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moreira-Barbosa, Catarina, Barros-Silva, Daniela, Costa-Pinheiro, Pedro, Torres-Ferreira, Jorge, Constâncio, Vera, Freitas, Rui, Oliveira, Jorge, Antunes, Luís, Henrique, Rui, Jerónimo, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206889/ https://www.ncbi.nlm.nih.gov/pubmed/30373654 http://dx.doi.org/10.1186/s13148-018-0564-2

Ejemplares similares

Early detection of the major male cancer types in blood-based liquid biopsies using a DNA methylation panel
por: Constâncio, Vera, et al.
Publicado: (2019)

Subtyping Lung Cancer Using DNA Methylation in Liquid Biopsies
por: Nunes, Sandra P., et al.
Publicado: (2019)

Circulating MicroRNAs as Biomarkers for Prostate Cancer Detection and Metastasis Development Prediction
por: Bidarra, David, et al.
Publicado: (2019)

DNA Methylation-Based Testing in Liquid Biopsies as Detection and Prognostic Biomarkers for the Four Major Cancer Types
por: Constâncio, Vera, et al.
Publicado: (2020)

MiR-193b promoter methylation accurately detects prostate cancer in urine sediments and miR-34b/c or miR-129-2 promoter methylation define subsets of clinically aggressive tumors
por: Torres-Ferreira, Jorge, et al.
Publicado: (2017)

Identification of clear cell renal cell carcinoma and oncocytoma using a three-gene promoter methylation panel
por: Pires-Luís, Ana Sílvia, et al.
Publicado: (2017)

Urinary Extracellular Vesicles as Potential Biomarkers for Urologic Cancers: An Overview of Current Methods and Advances
por: Lourenço, Catarina, et al.
Publicado: (2021)

Identification of a biomarker panel for improvement of prostate cancer diagnosis by volatile metabolic profiling of urine
por: Lima, Ana Rita, et al.
Publicado: (2019)

Application of Proteogenomics to Urine Analysis towards the Identification of Novel Biomarkers of Prostate Cancer: An Exploratory Study
por: Lima, Tânia, et al.
Publicado: (2022)

A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway
por: Freitas, Micaela, et al.
Publicado: (2018)

LiKidMiRs: A ddPCR-Based Panel of 4 Circulating miRNAs for Detection of Renal Cell Carcinoma
por: Sequeira, José Pedro, et al.
Publicado: (2022)

Shifting the Cancer Screening Paradigm: The Rising Potential of Blood-Based Multi-Cancer Early Detection Tests
por: Brito-Rocha, Tiago, et al.
Publicado: (2023)

Unveiling the World of Circulating and Exosomal microRNAs in Renal Cell Carcinoma
por: Sequeira, José Pedro, et al.
Publicado: (2021)

DNA methylation biomarkers accurately detect esophageal cancer prior and post neoadjuvant chemoradiation
por: Macedo‐Silva, Catarina, et al.
Publicado: (2023)

Deregulation of N6-Methyladenosine RNA Modification and Its Erasers FTO/ALKBH5 among the Main Renal Cell Tumor Subtypes
por: Guimarães-Teixeira, Catarina, et al.
Publicado: (2021)

DigiMir Test: Establishing a Novel Pipeline for MiR-371a Quantification Using Droplet Digital PCR in Liquid Biopsies From Testicular Germ Cell Tumor Patients
por: Sequeira, José Pedro, et al.
Publicado: (2022)

GC‐MS metabolomics‐based approach for the identification of a potential VOC‐biomarker panel in the urine of renal cell carcinoma patients
por: Monteiro, Márcia, et al.
Publicado: (2017)

A Multiplex Test Assessing MiR663a(me) and VIM(me) in Urine Accurately Discriminates Bladder Cancer from Inflammatory Conditions
por: Monteiro-Reis, Sara, et al.
Publicado: (2020)

MicroRNA promoter methylation: a new tool for accurate detection of urothelial carcinoma
por: Padrão, Nuno André, et al.
Publicado: (2017)

MicroRNA-375 plays a dual role in prostate carcinogenesis
por: Costa-Pinheiro, Pedro, et al.
Publicado: (2015)

Anti-neoplastic properties of hydralazine in prostate cancer
por: Graça, Inês, et al.
Publicado: (2014)

Emerging Lab-on-a-Chip Approaches for Liquid Biopsy in Lung Cancer: Status in CTCs and ctDNA Research and Clinical Validation
por: Carvalho, Ângela, et al.
Publicado: (2021)

Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors
por: Lobo, João, et al.
Publicado: (2021)

Cell-Free DNA Methylation of Selected Genes Allows for Early Detection of the Major Cancers in Women
por: Nunes, Sandra P., et al.
Publicado: (2018)

MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis
por: Barros-Silva, Daniela, et al.
Publicado: (2018)

Expression of EMT-Related Genes CAMK2N1 and WNT5A is increased in Locally Invasive and Metastatic Prostate Cancer
por: Carneiro, Isa, et al.
Publicado: (2019)

Differential methylation EPIC analysis discloses cisplatin-resistance related hypermethylation and tumor-specific heterogeneity within matched primary and metastatic testicular germ cell tumor patient tissue samples
por: Lobo, João, et al.
Publicado: (2021)

VIRMA-Dependent N6-Methyladenosine Modifications Regulate the Expression of Long Non-Coding RNAs CCAT1 and CCAT2 in Prostate Cancer
por: Barros-Silva, Daniela, et al.
Publicado: (2020)

Profiling DNA Methylation Based on Next-Generation Sequencing Approaches: New Insights and Clinical Applications
por: Barros-Silva, Daniela, et al.
Publicado: (2018)

Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors
por: Costa, Vera L, et al.
Publicado: (2007)

From Therapy Resistance to Targeted Therapies in Prostate Cancer
por: Moreira-Silva, Filipa, et al.
Publicado: (2022)

Downregulation of miR-130b~301b cluster is mediated by aberrant promoter methylation and impairs cellular senescence in prostate cancer
por: Ramalho-Carvalho, João, et al.
Publicado: (2017)

Epigenetic Markers for Molecular Detection of Prostate Cancer
por: Costa, Vera L., et al.
Publicado: (2007)

Liquid Biopsies in the Clinical Management of Germ Cell Tumor Patients: State-of-the-Art and Future Directions
por: Lobo, João, et al.
Publicado: (2021)

Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients
por: Maia, Sofia, et al.
Publicado: (2015)

A DNA methylation-based test for esophageal cancer detection
por: Salta, Sofia, et al.
Publicado: (2020)

MicroRNA-30a-5p(me): a novel diagnostic and prognostic biomarker for clear cell renal cell carcinoma in tissue and urine samples
por: Outeiro-Pinho, Gonçalo, et al.
Publicado: (2020)

The Critical Role of Hypoxic Microenvironment and Epigenetic Deregulation in Esophageal Cancer Radioresistance
por: Macedo-Silva, Catarina, et al.
Publicado: (2019)

Correction: MicroRNA-30a-5p(me): a novel diagnostic and prognostic biomarker for clear cell renal cell carcinoma in tissue and urine samples
por: Outeiro-Pinho, Gonçalo, et al.
Publicado: (2022)

A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA
por: Salta, Sofia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_55u2f6r5abpvfioe7bvvtv7bd9