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Hydroxychloroquine induced lung cancer suppression by enhancing chemo-sensitization and promoting the transition of M2-TAMs to M1-like macrophages

BACKGROUND: Lysosome-associated agents have been implicated as possible chemo-sensitizers and immune regulators for cancer chemotherapy. We investigated the potential roles and mechanisms of hydroxychloroquine (HCQ) in combination with chemotherapy in lung cancer treatment. METHODS: The effects of c...

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Detalles Bibliográficos
Autores principales:	Li, Yong, Cao, Fengjun, Li, Mingxing, Li, Pindong, Yu, Yuandong, Xiang, Longchao, Xu, Tao, Lei, Jinhua, Tai, Yun Yan, Zhu, Jianyong, Yang, Bingbing, Jiang, Yingpin, Zhang, Xiufang, Duo, Long, Chen, Ping, Yu, Xiongjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206903/ https://www.ncbi.nlm.nih.gov/pubmed/30373678 http://dx.doi.org/10.1186/s13046-018-0938-5

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