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Three Severe Cases of Viral Infections with Post-Kidney Transplantation Successfully Confirmed by Polymerase Chain Reaction and Flow Cytometry

Viral infections in patients with post-kidney transplantation are often difficult to diagnose as well as treat. We herein report three cases with severe viral infections after kidney transplantation. All their causative pathogens could be detected promptly by polymerase chain reaction and flow cytom...

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Autores principales: Nakanishi, Keita, Kaito, Hiroshi, Ogi, Miki, Takai, Denshi, Fujimura, Junya, Horinouchi, Tomoko, Yamamura, Tomohiko, Minamikawa, Shogo, Ninchoji, Takeshi, Nozu, Kandai, Imadome, Ken-Ichi, Iijima, Kazumoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206958/
https://www.ncbi.nlm.nih.gov/pubmed/30397600
http://dx.doi.org/10.1159/000493092
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author Nakanishi, Keita
Kaito, Hiroshi
Ogi, Miki
Takai, Denshi
Fujimura, Junya
Horinouchi, Tomoko
Yamamura, Tomohiko
Minamikawa, Shogo
Ninchoji, Takeshi
Nozu, Kandai
Imadome, Ken-Ichi
Iijima, Kazumoto
author_facet Nakanishi, Keita
Kaito, Hiroshi
Ogi, Miki
Takai, Denshi
Fujimura, Junya
Horinouchi, Tomoko
Yamamura, Tomohiko
Minamikawa, Shogo
Ninchoji, Takeshi
Nozu, Kandai
Imadome, Ken-Ichi
Iijima, Kazumoto
author_sort Nakanishi, Keita
collection PubMed
description Viral infections in patients with post-kidney transplantation are often difficult to diagnose as well as treat. We herein report three cases with severe viral infections after kidney transplantation. All their causative pathogens could be detected promptly by polymerase chain reaction and flow cytometry during the early stages of infection. These examinations would also be of great use to monitor therapeutic responses and disease activity. It is indeed true that no specific treatment is available for most of the viral infections, but we should be aware that some infections, such as Epstein-Barr virus infection, can be treatable with prompt and specific treatment, such as rituximab.
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spelling pubmed-62069582018-11-05 Three Severe Cases of Viral Infections with Post-Kidney Transplantation Successfully Confirmed by Polymerase Chain Reaction and Flow Cytometry Nakanishi, Keita Kaito, Hiroshi Ogi, Miki Takai, Denshi Fujimura, Junya Horinouchi, Tomoko Yamamura, Tomohiko Minamikawa, Shogo Ninchoji, Takeshi Nozu, Kandai Imadome, Ken-Ichi Iijima, Kazumoto Case Rep Nephrol Dial Case Report Viral infections in patients with post-kidney transplantation are often difficult to diagnose as well as treat. We herein report three cases with severe viral infections after kidney transplantation. All their causative pathogens could be detected promptly by polymerase chain reaction and flow cytometry during the early stages of infection. These examinations would also be of great use to monitor therapeutic responses and disease activity. It is indeed true that no specific treatment is available for most of the viral infections, but we should be aware that some infections, such as Epstein-Barr virus infection, can be treatable with prompt and specific treatment, such as rituximab. S. Karger AG 2018-09-25 /pmc/articles/PMC6206958/ /pubmed/30397600 http://dx.doi.org/10.1159/000493092 Text en Copyright © 2018 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Nakanishi, Keita
Kaito, Hiroshi
Ogi, Miki
Takai, Denshi
Fujimura, Junya
Horinouchi, Tomoko
Yamamura, Tomohiko
Minamikawa, Shogo
Ninchoji, Takeshi
Nozu, Kandai
Imadome, Ken-Ichi
Iijima, Kazumoto
Three Severe Cases of Viral Infections with Post-Kidney Transplantation Successfully Confirmed by Polymerase Chain Reaction and Flow Cytometry
title Three Severe Cases of Viral Infections with Post-Kidney Transplantation Successfully Confirmed by Polymerase Chain Reaction and Flow Cytometry
title_full Three Severe Cases of Viral Infections with Post-Kidney Transplantation Successfully Confirmed by Polymerase Chain Reaction and Flow Cytometry
title_fullStr Three Severe Cases of Viral Infections with Post-Kidney Transplantation Successfully Confirmed by Polymerase Chain Reaction and Flow Cytometry
title_full_unstemmed Three Severe Cases of Viral Infections with Post-Kidney Transplantation Successfully Confirmed by Polymerase Chain Reaction and Flow Cytometry
title_short Three Severe Cases of Viral Infections with Post-Kidney Transplantation Successfully Confirmed by Polymerase Chain Reaction and Flow Cytometry
title_sort three severe cases of viral infections with post-kidney transplantation successfully confirmed by polymerase chain reaction and flow cytometry
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206958/
https://www.ncbi.nlm.nih.gov/pubmed/30397600
http://dx.doi.org/10.1159/000493092
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