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Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children

BACKGROUND AND AIM: Capsule endoscopy (CE) offers a method of directly visualizing areas of the small bowel not accessible by conventional endoscopy. Some children are unable to swallow the capsule requiring endoscopic placement under general anesthesia. The aim of the present study was to identify...

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Autores principales: Burgess, Christopher J, McIntyre, Emma C, Withers, Geoffrey D, Ee, Looi C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207005/
https://www.ncbi.nlm.nih.gov/pubmed/30483526
http://dx.doi.org/10.1002/jgh3.12001
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author Burgess, Christopher J
McIntyre, Emma C
Withers, Geoffrey D
Ee, Looi C
author_facet Burgess, Christopher J
McIntyre, Emma C
Withers, Geoffrey D
Ee, Looi C
author_sort Burgess, Christopher J
collection PubMed
description BACKGROUND AND AIM: Capsule endoscopy (CE) offers a method of directly visualizing areas of the small bowel not accessible by conventional endoscopy. Some children are unable to swallow the capsule requiring endoscopic placement under general anesthesia. The aim of the present study was to identify any differences between children requiring endoscopic placement and those able to swallow the capsule. METHODS: Retrospective chart review of consecutive CE in a tertiary pediatric center was conducted. Patient demographics, outcomes, and complications between the two groups were noted. Paired t‐test comparing continuous variables and Fisher exact test for categorical data were used. RESULTS: A total of 104 CEs were performed in 88 patients, median age 12.8 (range: 1.6–18.5) years. Almost half, 49% (51/104), swallowed the capsule. Children requiring endoscopic placement were significantly younger (9.8 vs 14.2 years; P < 0.001), lighter (34.5 vs 54.9 kg; P < 0.0001), and had longer small intestinal transit time (308 vs 229 min; P < 0.0001). Positive findings were more likely in those who swallowed the capsule (50% vs 30%, P = 0.017), likely a reflection of the indications for procedure. Poor views were found in 30% (16/53) of patients in the endoscopic placement group due to iatrogenic bleeding from biopsies taken from concurrent procedures but did not affect outcome or subsequent patient management. CONCLUSIONS: CE is safe and well tolerated in children. Children requiring endoscopic placement were significantly younger, lighter, had longer small intestine transit time, and less likely to have positive findings. Concurrent biopsies during capsule placement increase the likelihood of inadequate views but did not affect outcome or management.
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spelling pubmed-62070052018-11-27 Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children Burgess, Christopher J McIntyre, Emma C Withers, Geoffrey D Ee, Looi C JGH Open Original Articles BACKGROUND AND AIM: Capsule endoscopy (CE) offers a method of directly visualizing areas of the small bowel not accessible by conventional endoscopy. Some children are unable to swallow the capsule requiring endoscopic placement under general anesthesia. The aim of the present study was to identify any differences between children requiring endoscopic placement and those able to swallow the capsule. METHODS: Retrospective chart review of consecutive CE in a tertiary pediatric center was conducted. Patient demographics, outcomes, and complications between the two groups were noted. Paired t‐test comparing continuous variables and Fisher exact test for categorical data were used. RESULTS: A total of 104 CEs were performed in 88 patients, median age 12.8 (range: 1.6–18.5) years. Almost half, 49% (51/104), swallowed the capsule. Children requiring endoscopic placement were significantly younger (9.8 vs 14.2 years; P < 0.001), lighter (34.5 vs 54.9 kg; P < 0.0001), and had longer small intestinal transit time (308 vs 229 min; P < 0.0001). Positive findings were more likely in those who swallowed the capsule (50% vs 30%, P = 0.017), likely a reflection of the indications for procedure. Poor views were found in 30% (16/53) of patients in the endoscopic placement group due to iatrogenic bleeding from biopsies taken from concurrent procedures but did not affect outcome or subsequent patient management. CONCLUSIONS: CE is safe and well tolerated in children. Children requiring endoscopic placement were significantly younger, lighter, had longer small intestine transit time, and less likely to have positive findings. Concurrent biopsies during capsule placement increase the likelihood of inadequate views but did not affect outcome or management. Wiley Publishing Asia Pty Ltd 2017-09-18 /pmc/articles/PMC6207005/ /pubmed/30483526 http://dx.doi.org/10.1002/jgh3.12001 Text en © 2017 The Authors. JGH Open: An open access journal of gastroenterology and hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Burgess, Christopher J
McIntyre, Emma C
Withers, Geoffrey D
Ee, Looi C
Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children
title Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children
title_full Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children
title_fullStr Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children
title_full_unstemmed Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children
title_short Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children
title_sort comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207005/
https://www.ncbi.nlm.nih.gov/pubmed/30483526
http://dx.doi.org/10.1002/jgh3.12001
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