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Effects of 3‐Bromo‐4,5‐dihydroisoxazole Derivatives on Nrf2 Activation and Heme Oxygenase‐1 Expression
Natural and synthetic electrophilic compounds have been shown to activate the antioxidant protective Nrf2 (nuclear factor erythroid 2‐related factor 2)/heme oxygenase‐1 (HO‐1) axis in cells and tissues. Here, we tested the ability of different isoxazoline‐based electrophiles to up‐regulate Nrf2/HO‐1...
Autores principales: | Pinto, Andrea, El Ali, Zeina, Moniot, Sébastien, Tamborini, Lucia, Steegborn, Clemens, Foresti, Roberta, De Micheli, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207109/ https://www.ncbi.nlm.nih.gov/pubmed/30397576 http://dx.doi.org/10.1002/open.201800185 |
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