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Effects of 3‐Bromo‐4,5‐dihydroisoxazole Derivatives on Nrf2 Activation and Heme Oxygenase‐1 Expression

Natural and synthetic electrophilic compounds have been shown to activate the antioxidant protective Nrf2 (nuclear factor erythroid 2‐related factor 2)/heme oxygenase‐1 (HO‐1) axis in cells and tissues. Here, we tested the ability of different isoxazoline‐based electrophiles to up‐regulate Nrf2/HO‐1...

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Detalles Bibliográficos
Autores principales: Pinto, Andrea, El Ali, Zeina, Moniot, Sébastien, Tamborini, Lucia, Steegborn, Clemens, Foresti, Roberta, De Micheli, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207109/
https://www.ncbi.nlm.nih.gov/pubmed/30397576
http://dx.doi.org/10.1002/open.201800185

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