Massive NGS data analysis reveals hundreds of potential novel gene fusions in human cell lines

BACKGROUND: Gene fusions derive from chromosomal rearrangements. The resulting chimeric transcripts are often endowed with oncogenic potential. Furthermore, they serve as diagnostic tools for the clinical classification of cancer subgroups with different prognosis and, in some cases, they can provid...

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Detalles Bibliográficos
Autores principales: Gioiosa, Silvia, Bolis, Marco, Flati, Tiziano, Massini, Annalisa, Garattini, Enrico, Chillemi, Giovanni, Fratelli, Maddalena, Castrignanò, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Data Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207142/
https://www.ncbi.nlm.nih.gov/pubmed/29860514
http://dx.doi.org/10.1093/gigascience/giy062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207142/
https://www.ncbi.nlm.nih.gov/pubmed/29860514
http://dx.doi.org/10.1093/gigascience/giy062

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