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Massive NGS data analysis reveals hundreds of potential novel gene fusions in human cell lines
BACKGROUND: Gene fusions derive from chromosomal rearrangements. The resulting chimeric transcripts are often endowed with oncogenic potential. Furthermore, they serve as diagnostic tools for the clinical classification of cancer subgroups with different prognosis and, in some cases, they can provid...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207142/ https://www.ncbi.nlm.nih.gov/pubmed/29860514 http://dx.doi.org/10.1093/gigascience/giy062 |