Cargando…

pH-responsive hybrid nanoparticle with enhanced dissociation characteristic for siRNA delivery

INTRODUCTION: Specific polo-like kinase (PLK1) silencing with small interface RNA (siRNA) may be an effective approach for PLK1-overexpressed lung cancer. However, low siRNA concentration into cytoplasm of tumor tissue severely limits its application. MATERIALS AND METHODS: In this study, a novel tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Menghao, Zhao, Xiufeng, Zhang, Jiulong, Pan, Shuang, Yang, Chunrong, Wei, Ying, Hu, Haiyang, Qiao, Mingxi, Chen, Dawei, Zhao, Xiuli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207255/ https://www.ncbi.nlm.nih.gov/pubmed/30498349 http://dx.doi.org/10.2147/IJN.S180119

Ejemplares similares

Mitochondria-targeted delivery of doxorubicin to enhance antitumor activity with HER-2 peptide-mediated multifunctional pH-sensitive DQAsomes
por: Shi, Menghao, et al.
Publicado: (2018)

Anti-EphA10 antibody-conjugated pH-sensitive liposomes for specific intracellular delivery of siRNA
por: Zang, Xinlong, et al.
Publicado: (2016)

Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine–docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo
por: Zhang, Jiulong, et al.
Publicado: (2018)

Combining immune checkpoint blockade with ATP-based immunogenic cell death amplifier for cancer chemo-immunotherapy
por: Zhang, Jiulong, et al.
Publicado: (2022)

Construction of Hierarchical-Targeting pH-Sensitive Liposomes to Reverse Chemotherapeutic Resistance of Cancer Stem-like Cells
por: Ba, Shuang, et al.
Publicado: (2021)

Preparation and evaluation of poly(l-histidine) based pH-sensitive micelles for intracellular delivery of doxorubicin against MCF-7/ADR cells
por: Jia, Nan, et al.
Publicado: (2017)

Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery
por: Cai, Rong-Qiao, et al.
Publicado: (2017)

Targeted Delivery of siRNA with pH-Responsive Hybrid Gold Nanostars for Cancer Treatment
por: Zhu, Hongyan, et al.
Publicado: (2017)

Advances in Lipid Nanoparticles for siRNA Delivery
por: Tam, Yuen Yi C., et al.
Publicado: (2013)

Calcium phosphate nanoparticles-based systems for siRNA delivery
por: Xu, Xiaochun, et al.
Publicado: (2016)

BSA Nanoparticles for siRNA Delivery: Coating Effects on Nanoparticle Properties, Plasma Protein Adsorption, and In Vitro siRNA Delivery
por: Yogasundaram, Haran, et al.
Publicado: (2012)

Redox/pH-Responsive 2-in-1 Chimeric Nanoparticles for the Co-Delivery of Doxorubicin and siRNA
por: Wu, Hsi-Chin, et al.
Publicado: (2021)

Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles
por: Castillo, Betzaida, et al.
Publicado: (2012)

Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles
por: Kummitha, China M, et al.
Publicado: (2012)

Cationic Magnetite Nanoparticles for Increasing siRNA Hybridization Rates
por: Prilepskii, Artur Y., et al.
Publicado: (2020)

Decoration of pH-sensitive copolymer micelles with tumor-specific peptide for enhanced cellular uptake of doxorubicin
por: Chen, Qing, et al.
Publicado: (2016)

Preparation Optimization of Bovine Serum Albumin Nanoparticles and Its Application for siRNA Delivery
por: Wang, Yifan, et al.
Publicado: (2021)

Hydrocarbon-Stapled Peptide Based-Nanoparticles for siRNA Delivery
por: Simon, Matthieu, et al.
Publicado: (2020)

Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells
por: Khare, Purva, et al.
Publicado: (2021)

Targeted Delivery of siRNA
por: Oliveira, Sabrina, et al.
Publicado: (2006)

Dendrimers for siRNA Delivery
por: Biswas, Swati, et al.
Publicado: (2013)

Dual pH-Responsive and Tumor-Targeted Nanoparticle-Mediated Anti-Angiogenesis siRNA Delivery for Tumor Treatment
por: Zhang, Xiangyang, et al.
Publicado: (2022)

Surface De-PEGylation Controls Nanoparticle-Mediated siRNA Delivery In Vitro and In Vivo
por: Zhu, Xi, et al.
Publicado: (2017)

Synthesis and Characterization of pH-Responsive PEG-Poly(β-Amino Ester) Block Copolymer Micelles as Drug Carriers to Eliminate Cancer Stem Cells
por: Li, Weinan, et al.
Publicado: (2020)

Enzyme-triggered PEGylated siRNA-nanoparticles for controlled release of siRNA
por: Yingyuad, Peerada, et al.
Publicado: (2014)

Degradable Lipid Nanoparticles with Predictable In Vivo siRNA Delivery Activity
por: Whitehead, Kathryn A., et al.
Publicado: (2014)

Polymeric nanoparticles for the delivery of siRNA and the partnership between WSU and UNIT
por: da Rocha, Sandro, et al.
Publicado: (2014)

Recent Developments in Nanoparticle-Based siRNA Delivery for Cancer Therapy
por: Lee, Jong-Min, et al.
Publicado: (2013)

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
por: Sahay, Gaurav, et al.
Publicado: (2013)

Oral delivery of siRNA lipid nanoparticles: Fate in the GI tract
por: Ball, Rebecca L., et al.
Publicado: (2018)

Cyclic Peptide-Capped Gold Nanoparticles for Enhanced siRNA Delivery
por: Shirazi, Amir Nasrolahi, et al.
Publicado: (2014)

Synthesis of Polymer-Lipid Nanoparticles by Microfluidic Focusing for siRNA Delivery
por: Li, Yujing, et al.
Publicado: (2016)

Polyphosphoester nanoparticles as biodegradable platform for delivery of multiple drugs and siRNA
por: Elzeny, Hadeel, et al.
Publicado: (2017)

Recent advances in siRNA delivery mediated by lipid-based nanoparticles
por: Yonezawa, Sei, et al.
Publicado: (2020)

Characterization of modified mesoporous silica nanoparticles as vectors for siRNA delivery
por: Slita, Anna, et al.
Publicado: (2018)

Novel Ellipsoid Chitosan-Phthalate Lecithin Nanoparticles for siRNA Delivery
por: Saeed, Ramzi Mukred, et al.
Publicado: (2021)

Tumor vasculature is a key determinant for the efficiency of nanoparticle-mediated siRNA delivery
por: Li, L, et al.
Publicado: (2012)

A Multifunctional Hybrid Nanocarrier for Non-Invasive siRNA Delivery to the Retina
por: Nishida, Shogo, et al.
Publicado: (2023)

Aptamer mediated siRNA delivery
por: Chu, Ted C., et al.
Publicado: (2006)

Pulmonary delivery of therapeutic siRNA
por: Lam, Jenny Ka-Wing, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2du3vg7pji76hbbob0lquhfv1c