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Adult Medulloblastoma: Occurrence of a Rare Event

Medulloblastoma is the most common type of aggressive pediatric primary brain malignancy. This case describes a 45-year-old Hispanic male with no significant past medical history who presented to the emergency department (ED) complaining of 15 days of 10/10 intractable headaches with one day of ligh...

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Autores principales: Kristeva, Mariya, Suprun, Andrey, Ghaffar, Ejaz, Wallis, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207282/
https://www.ncbi.nlm.nih.gov/pubmed/30397563
http://dx.doi.org/10.7759/cureus.3000
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author Kristeva, Mariya
Suprun, Andrey
Ghaffar, Ejaz
Wallis, Carolina
author_facet Kristeva, Mariya
Suprun, Andrey
Ghaffar, Ejaz
Wallis, Carolina
author_sort Kristeva, Mariya
collection PubMed
description Medulloblastoma is the most common type of aggressive pediatric primary brain malignancy. This case describes a 45-year-old Hispanic male with no significant past medical history who presented to the emergency department (ED) complaining of 15 days of 10/10 intractable headaches with one day of lightheadedness, confusion, and loss of balance. An urgent magnetic resonance imaging (MRI) of the brain revealed a 4.1 x 3.3 x 3.2 cm mass at the cerebellum, exerting a mass effect on the brainstem and mild tonsillar herniation. A pre-surgical physical exam revealed only a positive Babinski sign bilaterally with normal proprioception and cerebellar function. The intraoperative report concluded an undifferentiated neoplasm with a histological differential diagnosis of medulloblastoma, ependymoma, or other neuroepithelial neoplasms, suggesting a referral to a tertiary care center for further evaluation of the mass. Postsurgical complications included a severe vasogenic edema, causing obstructive hydrocephalus treated with frontal ventricular drainage, signs of meningitis treated with antibiotics, and hyponatremia. This case describes a rare occurrence of medulloblastoma in an adult patient, which required prompt diagnosis and urgent life-saving treatment.
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spelling pubmed-62072822018-11-05 Adult Medulloblastoma: Occurrence of a Rare Event Kristeva, Mariya Suprun, Andrey Ghaffar, Ejaz Wallis, Carolina Cureus Internal Medicine Medulloblastoma is the most common type of aggressive pediatric primary brain malignancy. This case describes a 45-year-old Hispanic male with no significant past medical history who presented to the emergency department (ED) complaining of 15 days of 10/10 intractable headaches with one day of lightheadedness, confusion, and loss of balance. An urgent magnetic resonance imaging (MRI) of the brain revealed a 4.1 x 3.3 x 3.2 cm mass at the cerebellum, exerting a mass effect on the brainstem and mild tonsillar herniation. A pre-surgical physical exam revealed only a positive Babinski sign bilaterally with normal proprioception and cerebellar function. The intraoperative report concluded an undifferentiated neoplasm with a histological differential diagnosis of medulloblastoma, ependymoma, or other neuroepithelial neoplasms, suggesting a referral to a tertiary care center for further evaluation of the mass. Postsurgical complications included a severe vasogenic edema, causing obstructive hydrocephalus treated with frontal ventricular drainage, signs of meningitis treated with antibiotics, and hyponatremia. This case describes a rare occurrence of medulloblastoma in an adult patient, which required prompt diagnosis and urgent life-saving treatment. Cureus 2018-07-18 /pmc/articles/PMC6207282/ /pubmed/30397563 http://dx.doi.org/10.7759/cureus.3000 Text en Copyright © 2018, Kristeva et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Kristeva, Mariya
Suprun, Andrey
Ghaffar, Ejaz
Wallis, Carolina
Adult Medulloblastoma: Occurrence of a Rare Event
title Adult Medulloblastoma: Occurrence of a Rare Event
title_full Adult Medulloblastoma: Occurrence of a Rare Event
title_fullStr Adult Medulloblastoma: Occurrence of a Rare Event
title_full_unstemmed Adult Medulloblastoma: Occurrence of a Rare Event
title_short Adult Medulloblastoma: Occurrence of a Rare Event
title_sort adult medulloblastoma: occurrence of a rare event
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207282/
https://www.ncbi.nlm.nih.gov/pubmed/30397563
http://dx.doi.org/10.7759/cureus.3000
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