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Benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community
BACKGROUND: Benzodiazepine and z-hypnotic prescribing has slowly decreased over the past 20 years, however long-term chronic prescribing still occurs and is at odds with prescribing guidance. OBJECTIVES: To identify the pattern of benzodiazepine and z-hypnotic prescribing in psychiatric inpatients a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Centro de Investigaciones y Publicaciones Farmaceuticas
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207358/ https://www.ncbi.nlm.nih.gov/pubmed/30416628 http://dx.doi.org/10.18549/PharmPract.2018.03.1256 |
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author | Johnson, Chris F. Nassr, Ola Ali Harpur, Catherine Kenicer, David Thom, Alex Akram, Gazala |
author_facet | Johnson, Chris F. Nassr, Ola Ali Harpur, Catherine Kenicer, David Thom, Alex Akram, Gazala |
author_sort | Johnson, Chris F. |
collection | PubMed |
description | BACKGROUND: Benzodiazepine and z-hypnotic prescribing has slowly decreased over the past 20 years, however long-term chronic prescribing still occurs and is at odds with prescribing guidance. OBJECTIVES: To identify the pattern of benzodiazepine and z-hypnotic prescribing in psychiatric inpatients at discharge and 12 months post-discharge. METHODS: Retrospective observational longitudinal cohort study of patients admitted to two adult psychiatric wards between June and November 2012 (inclusive) who were discharged with a prescription for a benzodiazepine or z-hypnotic drug. Routinely collected prescription data available from NHS Scotland Prescribing Information System was used to identify and follow community prescribing of benzodiazepine and z-hypnotics for a 12 month period post-discharge. Data were entered in Excel(®) and further analysed using SPSS 23. Ethical approval was not required for this service evaluation however Caldicott Guardian approval was sought and granted. RESULTS: Eighty patients were admitted during the study period however only those patients with a single admission were included for analysis (n=74). Thirty per cent (22/74) of patients were prescribed a benzodiazepine or z-hypnotics at discharge; 14 of whom received ‘long-term’ benzodiazepine and z-hypnotics i.e. continued use over the 12 month period. Seven patients received a combination of anxiolytics and hypnotics (e.g., diazepam plus temazepam or zopiclone). Long-term use was associated with a non-significant increase in median benzodiazepine or z-hypnotic dose, expressed as diazepam equivalents. CONCLUSIONS: One in three patients were prescribed a benzodiazepine or z-hypnotics at discharge with 1 in 5 receiving continuous long-term treatment (prescriptions) for 12 months post-discharge. As chronic long-term B-Z prescribing and use still remains an issue, future strategies using routine patient-level prescribing data may support prescribers to review and minimise inappropriate long-term prescribing. |
format | Online Article Text |
id | pubmed-6207358 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Centro de Investigaciones y Publicaciones Farmaceuticas |
record_format | MEDLINE/PubMed |
spelling | pubmed-62073582018-11-09 Benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community Johnson, Chris F. Nassr, Ola Ali Harpur, Catherine Kenicer, David Thom, Alex Akram, Gazala Pharm Pract (Granada) Original Research BACKGROUND: Benzodiazepine and z-hypnotic prescribing has slowly decreased over the past 20 years, however long-term chronic prescribing still occurs and is at odds with prescribing guidance. OBJECTIVES: To identify the pattern of benzodiazepine and z-hypnotic prescribing in psychiatric inpatients at discharge and 12 months post-discharge. METHODS: Retrospective observational longitudinal cohort study of patients admitted to two adult psychiatric wards between June and November 2012 (inclusive) who were discharged with a prescription for a benzodiazepine or z-hypnotic drug. Routinely collected prescription data available from NHS Scotland Prescribing Information System was used to identify and follow community prescribing of benzodiazepine and z-hypnotics for a 12 month period post-discharge. Data were entered in Excel(®) and further analysed using SPSS 23. Ethical approval was not required for this service evaluation however Caldicott Guardian approval was sought and granted. RESULTS: Eighty patients were admitted during the study period however only those patients with a single admission were included for analysis (n=74). Thirty per cent (22/74) of patients were prescribed a benzodiazepine or z-hypnotics at discharge; 14 of whom received ‘long-term’ benzodiazepine and z-hypnotics i.e. continued use over the 12 month period. Seven patients received a combination of anxiolytics and hypnotics (e.g., diazepam plus temazepam or zopiclone). Long-term use was associated with a non-significant increase in median benzodiazepine or z-hypnotic dose, expressed as diazepam equivalents. CONCLUSIONS: One in three patients were prescribed a benzodiazepine or z-hypnotics at discharge with 1 in 5 receiving continuous long-term treatment (prescriptions) for 12 months post-discharge. As chronic long-term B-Z prescribing and use still remains an issue, future strategies using routine patient-level prescribing data may support prescribers to review and minimise inappropriate long-term prescribing. Centro de Investigaciones y Publicaciones Farmaceuticas 2018 2018-09-26 /pmc/articles/PMC6207358/ /pubmed/30416628 http://dx.doi.org/10.18549/PharmPract.2018.03.1256 Text en Copyright: © Pharmacy Practice http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Johnson, Chris F. Nassr, Ola Ali Harpur, Catherine Kenicer, David Thom, Alex Akram, Gazala Benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community |
title | Benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community |
title_full | Benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community |
title_fullStr | Benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community |
title_full_unstemmed | Benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community |
title_short | Benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community |
title_sort | benzodiazepine and z-hypnotic prescribing from acute psychiatric inpatient discharge to long-term care in the community |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207358/ https://www.ncbi.nlm.nih.gov/pubmed/30416628 http://dx.doi.org/10.18549/PharmPract.2018.03.1256 |
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