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Chitosan-microcapsulated insulin alleviates mesenteric microcirculation dysfunction via modulating COX-2 and VCAM-1 expression in rats with diabetes mellitus

BACKGROUND: The study of the experiment was to display the therapeutic function of insulin-loaded chitosan (insulin/chitosan) on mesenteric microcirculation via down-regulating cyclooxygenase-2 (COX-2) and vascular cell adhesion molecule (VCAM-1) expressions in rats with diabetes mellitus (DM) as co...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Cao, Lijun, Suo, Yuan, Xu, Xiaoqin, Sun, Hui, Xu, Songao, Zhu, Xiangyun, Yu, Huijie, Cao, Weizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207390/
https://www.ncbi.nlm.nih.gov/pubmed/30498345
http://dx.doi.org/10.2147/IJN.S174030