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Tumor mutational burden is a determinant of immune-mediated survival in breast cancer
Mounting evidence supports a role for the immune system in breast cancer outcomes. The ability to distinguish highly immunogenic tumors susceptible to anti-tumor immunity from weakly immunogenic or inherently immune-resistant tumors would guide development of therapeutic strategies in breast cancer....
Autores principales: | Thomas, Alexandra, Routh, Eric D., Pullikuth, Ashok, Jin, Guangxu, Su, Jing, Chou, Jeff W., Hoadley, Katherine A., Print, Cristin, Knowlton, Nick, Black, Michael A., Demaria, Sandra, Wang, Ena, Bedognetti, Davide, Jones, Wendell D., Mehta, Gaurav A., Gatza, Michael L., Perou, Charles M., Page, David B., Triozzi, Pierre, Miller, Lance D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207420/ https://www.ncbi.nlm.nih.gov/pubmed/30386679 http://dx.doi.org/10.1080/2162402X.2018.1490854 |
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