Sialyltransferase ST3GAL1 promotes cell migration, invasion, and TGF-β1-induced EMT and confers paclitaxel resistance in ovarian cancer

Sialyltransferases transfer sialic acid to nascent oligosaccharides and are upregulated in cancer. The inhibition of sialyltransferases is emerging as a potential strategy to prevent metastasis in several cancers, including ovarian cancer. ST3GAL1 is a sialyltransferase that catalyzes the transfer o...

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Detalles Bibliográficos
Autores principales: Wu, Xin, Zhao, Junda, Ruan, Yuanyuan, Sun, Li, Xu, Congjian, Jiang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207573/
https://www.ncbi.nlm.nih.gov/pubmed/30375371
http://dx.doi.org/10.1038/s41419-018-1101-0