Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

Pressure overload induces a transition from cardiac hypertrophy to heart failure, but its underlying mechanisms remain elusive. Here we reconstruct a trajectory of cardiomyocyte remodeling and clarify distinct cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hy...

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Detalles Bibliográficos
Autores principales: Nomura, Seitaro, Satoh, Masahiro, Fujita, Takanori, Higo, Tomoaki, Sumida, Tomokazu, Ko, Toshiyuki, Yamaguchi, Toshihiro, Tobita, Takashige, Naito, Atsuhiko T., Ito, Masamichi, Fujita, Kanna, Harada, Mutsuo, Toko, Haruhiro, Kobayashi, Yoshio, Ito, Kaoru, Takimoto, Eiki, Akazawa, Hiroshi, Morita, Hiroyuki, Aburatani, Hiroyuki, Komuro, Issei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207673/
https://www.ncbi.nlm.nih.gov/pubmed/30375404
http://dx.doi.org/10.1038/s41467-018-06639-7

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