Standardized phytotherapic extracts rescue anomalous locomotion and electrophysiological responses of TDP-43 Drosophila melanogaster model of ALS

Findings from studies using animal models expressing amyotrophic lateral sclerosis (ALS) mutations in RNA-binding proteins, such as Transactive Response DNA-binding protein-43 (TDP-43), indicate that this protein, which is involved in multiple functions, including transcriptional regulation and pre-...

Descripción completa

Detalles Bibliográficos
Autores principales: Maccioni, Riccardo, Setzu, Maria Dolores, Talani, Giuseppe, Solari, Paolo, Kasture, Ameya, Sucic, Sonja, Porru, Simona, Muroni, Patrizia, Sanna, Enrico, Kasture, Sanjay, Acquas, Elio, Liscia, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207707/
https://www.ncbi.nlm.nih.gov/pubmed/30375462
http://dx.doi.org/10.1038/s41598-018-34452-1

Ejemplares similares

Ejemplares similares