Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses

Immunodeficient mice engrafted with human peripheral blood cells are promising tools for in vivo analysis of human patient individual immune responses. However, when human peripheral blood mononuclear cells (PBMCs) are transferred into NOG (NOD/Shi-scid, IL-2rg (null)) mice, severe graft versus host...

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Detalles Bibliográficos
Autores principales: Yaguchi, Tomonori, Kobayashi, Asuka, Inozume, Takashi, Morii, Kenji, Nagumo, Haruna, Nishio, Hiroshi, Iwata, Takashi, Ka, Yuyo, Katano, Ikumi, Ito, Ryoji, Ito, Mamoru, Kawakami, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207709/
https://www.ncbi.nlm.nih.gov/pubmed/29151581
http://dx.doi.org/10.1038/cmi.2017.106

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