Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) belongs to the CD clan of cysteine proteases. MALT1 is a unique enzyme among this clan because it recognizes the basic amino acid arginine in the P1 pocket. Previous studies carried out with natural amino acids revealed the s...

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Detalles Bibliográficos
Autores principales: Kasperkiewicz, Paulina, Kołt, Sonia, Janiszewski, Tomasz, Groborz, Katarzyna, Poręba, Marcin, Snipas, Scott J., Salvesen, Guy S., Drąg, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207715/
https://www.ncbi.nlm.nih.gov/pubmed/30375474
http://dx.doi.org/10.1038/s41598-018-34476-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207715/
https://www.ncbi.nlm.nih.gov/pubmed/30375474
http://dx.doi.org/10.1038/s41598-018-34476-7

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