Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever

A 51-year-old man visited our hospital with a main complaint of precordial pain, difficulty swallowing, and pyrexia. The patient was diagnosed with esophageal carcinosarcoma, based on the characteristic morphology noted on upper gastrointestinal endoscopy and histology tests, and he underwent surgic...

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Autores principales: Shioga, Taro, Matsushima, Shozo, Yamada, Eiji, Uchiyama, Takashi, Noto, Haruka, Suzuki, Daisuke, Nonaka, Takashi, Miyazawa, Shiro, Komatsu, Tatsuji, Yamamoto, Yuji, Sekido, Hitoshi, Niino, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207827/
https://www.ncbi.nlm.nih.gov/pubmed/29780130
http://dx.doi.org/10.2169/internalmedicine.0677-17
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author Shioga, Taro
Matsushima, Shozo
Yamada, Eiji
Uchiyama, Takashi
Noto, Haruka
Suzuki, Daisuke
Nonaka, Takashi
Miyazawa, Shiro
Komatsu, Tatsuji
Yamamoto, Yuji
Sekido, Hitoshi
Niino, Hitoshi
author_facet Shioga, Taro
Matsushima, Shozo
Yamada, Eiji
Uchiyama, Takashi
Noto, Haruka
Suzuki, Daisuke
Nonaka, Takashi
Miyazawa, Shiro
Komatsu, Tatsuji
Yamamoto, Yuji
Sekido, Hitoshi
Niino, Hitoshi
author_sort Shioga, Taro
collection PubMed
description A 51-year-old man visited our hospital with a main complaint of precordial pain, difficulty swallowing, and pyrexia. The patient was diagnosed with esophageal carcinosarcoma, based on the characteristic morphology noted on upper gastrointestinal endoscopy and histology tests, and he underwent surgical treatment. His preoperative blood granulocyte-colony stimulating factor (G-CSF) and interleukin-6 (IL-6) levels were high, and the surgical specimens were positive in both immunohistochemical tests; therefore, he was diagnosed with a G-CSF- and IL-6-producing tumor. When pyrexia is seen as a paraneoplastic symptom, it is important to consider and investigate the possibility of a cytokine-producing tumor.
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spelling pubmed-62078272018-10-31 Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever Shioga, Taro Matsushima, Shozo Yamada, Eiji Uchiyama, Takashi Noto, Haruka Suzuki, Daisuke Nonaka, Takashi Miyazawa, Shiro Komatsu, Tatsuji Yamamoto, Yuji Sekido, Hitoshi Niino, Hitoshi Intern Med Case Report A 51-year-old man visited our hospital with a main complaint of precordial pain, difficulty swallowing, and pyrexia. The patient was diagnosed with esophageal carcinosarcoma, based on the characteristic morphology noted on upper gastrointestinal endoscopy and histology tests, and he underwent surgical treatment. His preoperative blood granulocyte-colony stimulating factor (G-CSF) and interleukin-6 (IL-6) levels were high, and the surgical specimens were positive in both immunohistochemical tests; therefore, he was diagnosed with a G-CSF- and IL-6-producing tumor. When pyrexia is seen as a paraneoplastic symptom, it is important to consider and investigate the possibility of a cytokine-producing tumor. The Japanese Society of Internal Medicine 2018-05-18 2018-10-01 /pmc/articles/PMC6207827/ /pubmed/29780130 http://dx.doi.org/10.2169/internalmedicine.0677-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shioga, Taro
Matsushima, Shozo
Yamada, Eiji
Uchiyama, Takashi
Noto, Haruka
Suzuki, Daisuke
Nonaka, Takashi
Miyazawa, Shiro
Komatsu, Tatsuji
Yamamoto, Yuji
Sekido, Hitoshi
Niino, Hitoshi
Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever
title Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever
title_full Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever
title_fullStr Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever
title_full_unstemmed Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever
title_short Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever
title_sort esophageal carcinosarcoma that was diagnosed as a granulocyte-colony stimulating factor and interleukin-6-producing tumor with a tumor fever
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207827/
https://www.ncbi.nlm.nih.gov/pubmed/29780130
http://dx.doi.org/10.2169/internalmedicine.0677-17
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