Cargando…

Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis

Lymphocyte costimulation plays a central role in immunology, inflammation, and immunotherapy. The inducible T cell costimulator (ICOS) is expressed on T cells following peptide: MHC engagement with CD28 costimulation. The interaction of ICOS with its sole ligand, the inducible T cell costimulatory l...

Descripción completa

Detalles Bibliográficos
Autores principales:	O'Dwyer, Ronan, Kovaleva, Marina, Zhang, Jiquan, Steven, John, Cummins, Emma, Luxenberg, Deborah, Darmanin-Sheehan, Alfredo, Carvalho, Miguel F., Whitters, Matthew, Saunders, Kenneth, Barelle, Caroline J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207862/ https://www.ncbi.nlm.nih.gov/pubmed/30417018 http://dx.doi.org/10.1155/2018/4089459

Ejemplares similares

Therapeutic Potential of Shark Anti-ICOSL VNAR Domains is Exemplified in a Murine Model of Autoimmune Non-Infectious Uveitis
por: Kovaleva, Marina, et al.
Publicado: (2017)

Inducible costimulator ligand (ICOSL) on CD19(+) B cells is involved in immunopathological damage of rheumatoid arthritis (RA)
por: Ding, Sisi, et al.
Publicado: (2022)

Loss of human ICOSL results in combined immunodeficiency
por: Roussel, Lucie, et al.
Publicado: (2018)

Osteopontin binds ICOSL promoting tumor metastasis
por: Raineri, Davide, et al.
Publicado: (2020)

The ICOS–ICOSL pathway tunes thymic selection
por: Dong, Mengqi, et al.
Publicado: (2022)

Effect of Cellular-Based Artificial Antigen Presenting Cells Expressing ICOSL, in T-cell Subtypes Differentiation and Activation
por: Talebi, Mehdi, et al.
Publicado: (2021)

Expression of ICOSL is associated with decreased survival in invasive breast cancer
por: Wang, Bin, et al.
Publicado: (2019)

Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion
por: Angulo, Guillem, et al.
Publicado: (2021)

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development
por: Ubah, Obinna C., et al.
Publicado: (2017)

The role of inducible costimulatory molecular ligand (ICOSL) in children with neutrophilic asthma
por: Dong, Heting, et al.
Publicado: (2020)

ICOSL Stimulation by ICOS-Fc Accelerates Cutaneous Wound Healing In Vivo
por: Stoppa, Ian, et al.
Publicado: (2022)

The ICOSL Expression Predicts Better Prognosis for Nasopharyngeal Carcinoma via Enhancing Oncoimmunity
por: Zhang, Geng, et al.
Publicado: (2020)

Collagenous colitis and rheumatoid arthritis: is there a connection?
por: Wollheim, F, et al.
Publicado: (2003)

Autoimmunity to citrullinated type II collagen in rheumatoid arthritis
por: Yoshida, Mamoru, et al.
Publicado: (2006)

Collagen‐induced arthritis as an animal model of rheumatoid cachexia
por: Alabarse, Paulo V.G., et al.
Publicado: (2018)

S35. Investigating the ICOS/ICOSL pathway as a target for combination therapy with anti-CTLA-4
por: Sharma, P
Publicado: (2014)

Th17 Down-regulation Is Involved in Reduced Progression of Schistosomiasis Fibrosis in ICOSL KO Mice
por: Wang, Bo, et al.
Publicado: (2015)

The Spontaneous Autoimmune Neuromyopathy in ICOSL(−/−) NOD Mice Is CD4(+) T-Cell and Interferon-γ Dependent
por: Briet, Claire, et al.
Publicado: (2017)

Therapeutic Effect of Exogenous Regulatory T Cells on Collagen-induced Arthritis and Rheumatoid Arthritis
por: Li, Shutong, et al.
Publicado: (2020)

Role of methotrexate chronotherapy in collagen-induced rheumatoid arthritis in rats
por: Wang, X., et al.
Publicado: (2016)

Collagen Autoantibodies and Their Relationship to CCP Antibodies and Rheumatoid Factor in the Progression of Early Rheumatoid Arthritis
por: Whittingham, Senga F., et al.
Publicado: (2017)

ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells
por: Lee, Hyun-Joo, et al.
Publicado: (2017)

PD-L1 and ICOSL discriminate human Secretory and Helper dendritic cells in cancer, allergy and autoimmunity
por: Hoffmann, Caroline, et al.
Publicado: (2022)

Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases
por: Bellan, Mattia, et al.
Publicado: (2022)

Differential Modulation of Human M1 and M2 Macrophage Activity by ICOS-Mediated ICOSL Triggering
por: Gigliotti, Casimiro Luca, et al.
Publicado: (2023)

Involvement of CD40-CD40L and ICOS-ICOSL in the development of chronic rhinosinusitis by targeting eosinophils
por: Zhou, Aina, et al.
Publicado: (2023)

Recombinant interferon alpha 2b in rheumatoid arthritis: good antigen for rheumatoid arthritis antibodies
por: Ali Khan, Wahid
Publicado: (2018)

Anti-Inflammatory Effects of HDL in Mice With Rheumatoid Arthritis Induced by Collagen
por: Wang, Yunlong, et al.
Publicado: (2018)

Paradoxical Duel Role of Collagen in Rheumatoid Arthritis: Cause of Inflammation and Treatment
por: Elango, Jeevithan, et al.
Publicado: (2022)

Cartilage-Related Collagens in Osteoarthritis and Rheumatoid Arthritis: From Pathogenesis to Therapeutics
por: Ouyang, Ziwei, et al.
Publicado: (2023)

Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand
por: Pepple, Kathryn L., et al.
Publicado: (2019)

Dysregulation of Innate Lymphoid Cells in Patients with Active Rheumatoid Arthritis and Mice with Collagen-Induced Arthritis
por: Yang, Fengfan, et al.
Publicado: (2021)

New Studies of Pathogenesis of Rheumatoid Arthritis with Collagen-Induced and Collagen Antibody-Induced Arthritis Models: New Insight Involving Bacteria Flora
por: Hashida, Ryoichi, et al.
Publicado: (2021)

The rheumatoid arthritis specific Sa antigen is citrullinated vimentin
por: Vossenaar, ER, et al.
Publicado: (2004)

Yoga, rheumatoid arthritis & human leukocyte antigen-G
por: Mittal, Balraj
Publicado: (2022)

MicroRNA-146a regulates ICOS–ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres
por: Pratama, Alvin, et al.
Publicado: (2015)

Immunofibroblasts regulate LTα3 expression in tertiary lymphoid structures in a pathway dependent on ICOS/ICOSL interaction
por: Nayar, Saba, et al.
Publicado: (2022)

Myeloid-derived suppressor cells promote the formation of abdominal aortic aneurysms through the IL-3-ICOSL-ICOS axis
por: Lu, Li, et al.
Publicado: (2023)

Non-Alcoholic Steatohepatitis (NASH) – A Review of a Crowded Clinical Landscape, Driven by a Complex Disease
por: Fraile, Julia M, et al.
Publicado: (2021)

Antibodies against the CB10 fragment of type II collagen in rheumatoid arthritis
por: Cook, Andrew D, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_td6t0q4l2h42std9f757plp8mi