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Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis

Lymphocyte costimulation plays a central role in immunology, inflammation, and immunotherapy. The inducible T cell costimulator (ICOS) is expressed on T cells following peptide: MHC engagement with CD28 costimulation. The interaction of ICOS with its sole ligand, the inducible T cell costimulatory l...

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Detalles Bibliográficos
Autores principales:	O'Dwyer, Ronan, Kovaleva, Marina, Zhang, Jiquan, Steven, John, Cummins, Emma, Luxenberg, Deborah, Darmanin-Sheehan, Alfredo, Carvalho, Miguel F., Whitters, Matthew, Saunders, Kenneth, Barelle, Caroline J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207862/ https://www.ncbi.nlm.nih.gov/pubmed/30417018 http://dx.doi.org/10.1155/2018/4089459

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