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Nucleotide excision repair is a predictor of early relapse in pediatric acute lymphoblastic leukemia

BACKGROUND: Nucleotide Excision Repair (NER) is a major pathway of mammalian DNA repair that is associated with drug resistance and has not been well characterized in acute lymphoblastic leukemia (ALL). The objective of this study was to explore the role of NER in relapsed ALL patients. We hypothesi...

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Detalles Bibliográficos
Autores principales: Ibrahim, Omar M., As Sobeai, Homood M., Grant, Stephen G., Latimer, Jean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208034/
https://www.ncbi.nlm.nih.gov/pubmed/30376844
http://dx.doi.org/10.1186/s12920-018-0422-2