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Nucleotide excision repair is a predictor of early relapse in pediatric acute lymphoblastic leukemia
BACKGROUND: Nucleotide Excision Repair (NER) is a major pathway of mammalian DNA repair that is associated with drug resistance and has not been well characterized in acute lymphoblastic leukemia (ALL). The objective of this study was to explore the role of NER in relapsed ALL patients. We hypothesi...
Autores principales: | Ibrahim, Omar M., As Sobeai, Homood M., Grant, Stephen G., Latimer, Jean J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208034/ https://www.ncbi.nlm.nih.gov/pubmed/30376844 http://dx.doi.org/10.1186/s12920-018-0422-2 |
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