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Over-expressed lncRNA HOTAIRM1 promotes tumor growth and invasion through up-regulating HOXA1 and sequestering G9a/EZH2/Dnmts away from the HOXA1 gene in glioblastoma multiforme

BACKGROUND: Glioblastoma multiforme (GBM) is the common primary brain tumor classified the most malignant glioma. Long non-coding RNAs (LncRNAs) are important epigenetic regulators with critical roles in cancer initiation and progression. LncRNA HOTAIRM1 transcribes from the antisense strand of HOXA...

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Detalles Bibliográficos
Autores principales:	Li, Qi, Dong, Chengya, Cui, Jiayue, Wang, Yubo, Hong, Xinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208043/ https://www.ncbi.nlm.nih.gov/pubmed/30376874 http://dx.doi.org/10.1186/s13046-018-0941-x

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