Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study

BACKGROUND: Drug repurposing has been an interesting and cost-effective approach, especially for neglected diseases, such as Chagas disease. METHODS: In this work, we studied the activity of the antidepressant drug sertraline against Trypanosoma cruzi trypomastigotes and intracellular amastigotes of...

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Detalles Bibliográficos
Autores principales: Ferreira, Daiane Dias, Mesquita, Juliana Tonini, da Costa Silva, Thais Alves, Romanelli, Maiara Maria, da Gama Jaen Batista, Denise, da Silva, Cristiane França, da Gama, Aline Nefertiti Silva, Neves, Bruno Junior, Melo-Filho, Cleber Camilo, Correia Soeiro, Maria de Nazare, Andrade, Carolina Horta, Tempone, Andre Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208092/
https://www.ncbi.nlm.nih.gov/pubmed/30450114
http://dx.doi.org/10.1186/s40409-018-0165-8

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