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Selective sweeps and genetic lineages of Plasmodium falciparum multi-drug resistance (pfmdr1) gene in Kenya

BACKGROUND: There are concerns that resistance to artemisinin-based combination therapy might emerge in Kenya and sub-Saharan Africa (SSA) in the same pattern as was with chloroquine and sulfadoxine–pyrimethamine. Single nucleotide polymorphisms (SNPs) in critical alleles of pfmdr1 gene have been as...

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Detalles Bibliográficos
Autores principales:	Muiruri, Peninah, Juma, Denis W., Ingasia, Luicer A., Chebon, Lorna J., Opot, Benjamin, Ngalah, Bidii S., Cheruiyot, Jelagat, Andagalu, Ben, Akala, Hoseah M., Nyambati, Venny C. S., Ng’ang’a, Joseph K., Kamau, Edwin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208105/ https://www.ncbi.nlm.nih.gov/pubmed/30376843 http://dx.doi.org/10.1186/s12936-018-2534-8

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