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A recombinant conjugated pneumococcal vaccine that protects against murine infections with a similar efficacy to Prevnar-13
The pneumococcal conjugate vaccine (PCV) strongly protects against vaccine serotypes, but the rapid expansion of non-vaccine serotype disease and the vaccine’s high expense has reduced its overall impact. We have developed Protein Glycan Coupling Technology (PGCT) as a flexible methodology for makin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208403/ https://www.ncbi.nlm.nih.gov/pubmed/30393571 http://dx.doi.org/10.1038/s41541-018-0090-4 |