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Peroxiredoxin 1 silencing inhibited the growth and promoted apoptosis of pancreatic cancer cells via targeting FOXO3 gene

OBJECTIVE: Our study aimed to investigate the interaction between peroxiredoxin 1 (Prx1) and forkhead box O3 (FOXO3) and to explore the role of PI3K/AKT pathway in the development of pancreatic cancer. MATERIAL AND METHODS: Human pancreatic normal cells HPDE6-C7 and pancreatic cancer cells PANC-1 we...

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Detalles Bibliográficos
Autores principales:	Sun, Xianchun, Kong, Lingting, Li, Bingshu, Zhang, Yan, Yang, Haiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208491/ https://www.ncbi.nlm.nih.gov/pubmed/30464602 http://dx.doi.org/10.2147/CMAR.S177243

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