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Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population
OBJECTIVES: In order to address the current deficiency of health utility evidence relevant for economic evaluations involving treatments for rheumatoid arthritis (RA) in the Chinese setting, this study aims to develop a mapping algorithm linking the Health Assessment Questionnaire (HAQ) and EQ-5D-5L...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208580/ https://www.ncbi.nlm.nih.gov/pubmed/29974382 http://dx.doi.org/10.1007/s11136-018-1925-1 |
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author | Patton, Thomas Hu, Hao Luan, Luan Yang, Keqin Li, Shu-Chuen |
author_facet | Patton, Thomas Hu, Hao Luan, Luan Yang, Keqin Li, Shu-Chuen |
author_sort | Patton, Thomas |
collection | PubMed |
description | OBJECTIVES: In order to address the current deficiency of health utility evidence relevant for economic evaluations involving treatments for rheumatoid arthritis (RA) in the Chinese setting, this study aims to develop a mapping algorithm linking the Health Assessment Questionnaire (HAQ) and EQ-5D-5L in a Chinese population of patients with RA. METHODS: An estimation sample was obtained from a cross-sectional study that collected HAQ, the pain Visual Analogue Scale, and EQ-5D-5L in RA patients in two tertiary referral hospitals in China. Mapping algorithms were derived in this study using two alternative regression methods: the beta regression and a multivariate ordered probit regression. The internal validity of the mapping algorithms was assessed in each case by calculating predictive performance using a bootstrapping procedure. RESULTS: Of the several algorithms developed using these data, predictive performance was shown to be better when VAS pain was included as a predictor and when the multivariate ordered probit regression method was used, rather than the beta regression method. The algorithms developed were shown to be comparable, in terms of predictive performance, to existing mapping studies despite the small sample size of the estimation data. CONCLUSION: It is hoped that the availability of these algorithms will facilitate the development of cost-effectiveness studies evaluating RA treatments in the Chinese health care setting. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11136-018-1925-1) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-6208580 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-62085802018-11-09 Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population Patton, Thomas Hu, Hao Luan, Luan Yang, Keqin Li, Shu-Chuen Qual Life Res Article OBJECTIVES: In order to address the current deficiency of health utility evidence relevant for economic evaluations involving treatments for rheumatoid arthritis (RA) in the Chinese setting, this study aims to develop a mapping algorithm linking the Health Assessment Questionnaire (HAQ) and EQ-5D-5L in a Chinese population of patients with RA. METHODS: An estimation sample was obtained from a cross-sectional study that collected HAQ, the pain Visual Analogue Scale, and EQ-5D-5L in RA patients in two tertiary referral hospitals in China. Mapping algorithms were derived in this study using two alternative regression methods: the beta regression and a multivariate ordered probit regression. The internal validity of the mapping algorithms was assessed in each case by calculating predictive performance using a bootstrapping procedure. RESULTS: Of the several algorithms developed using these data, predictive performance was shown to be better when VAS pain was included as a predictor and when the multivariate ordered probit regression method was used, rather than the beta regression method. The algorithms developed were shown to be comparable, in terms of predictive performance, to existing mapping studies despite the small sample size of the estimation data. CONCLUSION: It is hoped that the availability of these algorithms will facilitate the development of cost-effectiveness studies evaluating RA treatments in the Chinese health care setting. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11136-018-1925-1) contains supplementary material, which is available to authorized users. Springer International Publishing 2018-07-04 2018 /pmc/articles/PMC6208580/ /pubmed/29974382 http://dx.doi.org/10.1007/s11136-018-1925-1 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Article Patton, Thomas Hu, Hao Luan, Luan Yang, Keqin Li, Shu-Chuen Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population |
title | Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population |
title_full | Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population |
title_fullStr | Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population |
title_full_unstemmed | Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population |
title_short | Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population |
title_sort | mapping between haq-di and eq-5d-5l in a chinese patient population |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208580/ https://www.ncbi.nlm.nih.gov/pubmed/29974382 http://dx.doi.org/10.1007/s11136-018-1925-1 |
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