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Erythropoietin-mediated activation of aquaporin-4 channel for the treatment of experimental hydrocephalus

OBJECTIVE: In this study, we investigate a neuroprotective agent, erythropoietin (EPO), in animal hydrocephalus model and its potential reversal effects on hydrocephalus by altering the expression of aquaporin-4 (AQP4). METHODS: Obstructive hydrocephalus was induced in 2-week-old rat pups by injecti...

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Detalles Bibliográficos
Autores principales: Rizwan Siddiqui, M., Attar, Furqan, Mohanty, Vineet, Kim, Kwang Sik, Shekhar Mayanil, C., Tomita, Tadanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208663/
https://www.ncbi.nlm.nih.gov/pubmed/29982881
http://dx.doi.org/10.1007/s00381-018-3865-z