Uncoupling protein 3 deficiency impairs myocardial fatty acid oxidation and contractile recovery following ischemia/reperfusion

Patients with insulin resistance and type 2 diabetes have poor cardiac outcomes following myocardial infarction (MI). The mitochondrial uncoupling protein 3 (UCP3) is down-regulated in the heart with insulin resistance. We hypothesized that decreased UCP3 levels contribute to poor cardiac recovery f...

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Detalles Bibliográficos
Autores principales: Edwards, Kristin S., Ashraf, Sadia, Lomax, Tyler M., Wiseman, Jessica M., Hall, Michael E., Gava, Fabio N., Hall, John E., Hosler, Jonathan P., Harmancey, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208686/
https://www.ncbi.nlm.nih.gov/pubmed/30374710
http://dx.doi.org/10.1007/s00395-018-0707-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208686/
https://www.ncbi.nlm.nih.gov/pubmed/30374710
http://dx.doi.org/10.1007/s00395-018-0707-9

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