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Uncoupling protein 3 deficiency impairs myocardial fatty acid oxidation and contractile recovery following ischemia/reperfusion

Patients with insulin resistance and type 2 diabetes have poor cardiac outcomes following myocardial infarction (MI). The mitochondrial uncoupling protein 3 (UCP3) is down-regulated in the heart with insulin resistance. We hypothesized that decreased UCP3 levels contribute to poor cardiac recovery f...

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Detalles Bibliográficos
Autores principales:	Edwards, Kristin S., Ashraf, Sadia, Lomax, Tyler M., Wiseman, Jessica M., Hall, Michael E., Gava, Fabio N., Hall, John E., Hosler, Jonathan P., Harmancey, Romain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Contribution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208686/ https://www.ncbi.nlm.nih.gov/pubmed/30374710 http://dx.doi.org/10.1007/s00395-018-0707-9

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