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Leptin gene polymorphism affects leptin level in childhood asthma

BACKGROUND: Leptin may induce inflammation in asthma by activation of Th2 cells. It has also been demonstrated that leptin expression increases upon inflammation and that asthmatic patients show increased serum leptin levels. We hypothesized that the polymorphism in leptin (LEP) and leptin receptor...

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Detalles Bibliográficos
Autores principales: Szczepankiewicz, Dawid, Sobkowiak, Paulina, Narożna, Beata, Wojsyk-Banaszak, Irena, Bręborowicz, Anna, Szczepankiewicz, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Childrens Hospital, Zhejiang University School of Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208747/
https://www.ncbi.nlm.nih.gov/pubmed/30203371
http://dx.doi.org/10.1007/s12519-018-0182-2