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eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B
The initiator tRNA (Met-tRNA(i)(Met)) at the P site of the small ribosomal subunit plays an important role in the recognition of an mRNA start codon. In bacteria, the initiator tRNA carrier, IF2, facilitates the positioning of Met-tRNA(i)(Met) on the small ribosomal subunit. Eukarya contain the Met-...
Autores principales: | Kim, Eunah, Kim, Joon Hyun, Seo, Keunhee, Hong, Ka Young, An, Seon Woo A., Kwon, Junyoung, Lee, Seung-Jae V., Jang, Sung Key |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208778/ https://www.ncbi.nlm.nih.gov/pubmed/30019215 http://dx.doi.org/10.1007/s00018-018-2870-4 |
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