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Clinical translation of [(18)F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer

BACKGROUND: Effective anticancer therapy is thought to involve induction of tumour cell death through apoptosis and/or necrosis. [(18)F]ICMT-11, an isatin sulfonamide caspase-3/7-specific radiotracer, has been developed for PET imaging and shown to have favourable dosimetry, safety, and biodistribut...

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Detalles Bibliográficos
Autores principales:	Dubash, S. R., Merchant, S., Heinzmann, K., Mauri, F., Lavdas, I., Inglese, M., Kozlowski, K., Rama, N., Masrour, N., Steel, J. F., Thornton, A., Lim, A. K., Lewanski, C., Cleator, S., Coombes, R. C., Kenny, Laura, Aboagye, Eric O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208806/ https://www.ncbi.nlm.nih.gov/pubmed/30259091 http://dx.doi.org/10.1007/s00259-018-4098-9

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