PDGF-BB regulates splitting angiogenesis in skeletal muscle by limiting VEGF-induced endothelial proliferation

VEGF induces normal or aberrant angiogenesis depending on its dose in the microenvironment around each producing cell in vivo. This transition depends on the balance between VEGF-induced endothelial stimulation and PDGF-BB-mediated pericyte recruitment, and co-expression of PDGF-BB normalizes aberra...

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Detalles Bibliográficos
Autores principales: Gianni-Barrera, R., Butschkau, A., Uccelli, A., Certelli, A., Valente, P., Bartolomeo, M., Groppa, E., Burger, M. G., Hlushchuk, R., Heberer, M., Schaefer, D. J., Gürke, L., Djonov, V., Vollmar, B., Banfi, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208885/
https://www.ncbi.nlm.nih.gov/pubmed/30014172
http://dx.doi.org/10.1007/s10456-018-9634-5

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