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Assessment of the direct effects of DDAH I on tumour angiogenesis in vivo
Nitric oxide (NO) has been strongly implicated in glioma progression and angiogenesis. The endogenous inhibitors of NO synthesis, asymmetric dimethylarginine (ADMA) and N-monomethyl-l-arginine (l-NMMA), are metabolized by dimethylarginine dimethylaminohydrolase (DDAH), and hence, DDAH is an intracel...
Autores principales: | Papaevangelou, Efthymia, Boult, Jessica K. R., Whitley, Guy S., Robinson, Simon P., Howe, Franklyn A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208893/ https://www.ncbi.nlm.nih.gov/pubmed/29721731 http://dx.doi.org/10.1007/s10456-018-9617-6 |
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