Comparison of central laboratory assessments of ER, PR, HER2, and Ki67 by IHC/FISH and the corresponding mRNAs (ESR1, PGR, ERBB2, and MKi67) by RT-qPCR on an automated, broadly deployed diagnostic platform

PURPOSE: The methods (IHC/FISH) typically used to assess ER, PR, HER2, and Ki67 in FFPE specimens from breast cancer patients are difficult to set up, perform, and standardize for use in low and middle-income countries. Use of an automated diagnostic platform (GeneXpert®) and assay (Xpert® Breast Ca...

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Detalles Bibliográficos
Autores principales: Wu, Natalie C., Wong, Wendy, Ho, Kenneth E., Chu, Victor C., Rizo, Annaliza, Davenport, Simon, Kelly, Devon, Makar, Rosemary, Jassem, Jacek, Duchnowska, Renata, Biernat, Wojciech, Radecka, Barbara, Fujita, Tomoyuki, Klein, Jonathan L., Stonecypher, Mark, Ohta, Shoichiro, Juhl, Hartmut, Weidler, Jodi M., Bates, Michael, Press, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208911/
https://www.ncbi.nlm.nih.gov/pubmed/30120700
http://dx.doi.org/10.1007/s10549-018-4889-5

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