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A hydroquinone-specific screening system for directed P450 evolution
The direct hydroxylation of benzene to hydroquinone (HQ) under mild reaction conditions is a challenging task for chemical catalysts. Cytochrome P450 (CYP) monooxygenases are known to catalyze the oxidation of a variety of aromatic compounds with atmospheric dioxygen. Protein engineering campaigns l...
Autores principales: | Weingartner, Alexandra M., Sauer, Daniel F., Dhoke, Gaurao V., Davari, Mehdi D., Ruff, Anna Joëlle, Schwaneberg, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208966/ https://www.ncbi.nlm.nih.gov/pubmed/30191291 http://dx.doi.org/10.1007/s00253-018-9328-3 |
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