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Critical assessment of different methods for quantitative measurement of metallodrug-protein associations
Quantitative screening for potential drug–protein binding is an essential step in developing novel metal-based anticancer drugs. ICP–MS approaches are at the core of this task; however, many applications lack in the capability of large-scale high-throughput screenings and proper validation. In this...
Autores principales: | Galvez, Luis, Theiner, Sarah, Grabarics, Márkó, Kowol, Christian R., Keppler, Bernhard K., Hann, Stephan, Koellensperger, Gunda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208971/ https://www.ncbi.nlm.nih.gov/pubmed/30155703 http://dx.doi.org/10.1007/s00216-018-1328-8 |
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