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Cystatin C takes part in melanoma-microglia cross-talk: possible implications for brain metastasis

The development of melanoma brain metastasis is largely dependent on mutual interactions between the melanoma cells and cells in the brain microenvironment. Here, we report that the extracellular cysteine protease inhibitor cystatin C (CysC) is involved in these interactions. Microglia-derived facto...

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Detalles Bibliográficos
Autores principales: Moshe, Adi, Izraely, Sivan, Sagi-Assif, Orit, Prakash, Roshini, Telerman, Alona, Meshel, Tsipi, Carmichael, Thomas, Witz, Isaac P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208992/
https://www.ncbi.nlm.nih.gov/pubmed/29722001
http://dx.doi.org/10.1007/s10585-018-9891-0