Simultaneous induction of dispersed and clustered DNA lesions compromises DNA damage response in human peripheral blood lymphocytes

Due to its ability to induce DNA damage in a space and time controlled manner, ionising radiation is a unique tool for studying the mechanisms of DNA repair. The biological effectiveness of ionising radiation is related to the ionisation density which is defined by the linear energy transfer (LET)....

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Detalles Bibliográficos
Autores principales: Cheng, Lei, Brzozowska, Beata, Sollazzo, Alice, Lundholm, Lovisa, Lisowska, Halina, Haghdoost, Siamak, Wojcik, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209146/
https://www.ncbi.nlm.nih.gov/pubmed/30379881
http://dx.doi.org/10.1371/journal.pone.0204068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209146/
https://www.ncbi.nlm.nih.gov/pubmed/30379881
http://dx.doi.org/10.1371/journal.pone.0204068

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