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Comparison of normalization approaches for gene expression studies completed with high-throughput sequencing

Normalization of RNA-Seq data has proven essential to ensure accurate inferences and replication of findings. Hence, various normalization methods have been proposed for various technical artifacts that can be present in high-throughput sequencing transcriptomic studies. In this study, we set out to...

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Detalles Bibliográficos
Autores principales: Abbas-Aghababazadeh, Farnoosh, Li, Qian, Fridley, Brooke L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209231/
https://www.ncbi.nlm.nih.gov/pubmed/30379879
http://dx.doi.org/10.1371/journal.pone.0206312