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Delayed first active-phase meal, a breakfast-skipping model, led to increased body weight and shifted the circadian oscillation of the hepatic clock and lipid metabolism-related genes in rats fed a high-fat diet
The circadian clock is closely related to human health, such as metabolic syndrome and cardiovascular disease. Our previous study revealed that irregular feeding induced abnormal lipid metabolism with disruption of the hepatic circadian clock. We hypothesized that breakfast skipping induces lipid ab...
Autores principales: | Shimizu, Hatsumi, Hanzawa, Fumiaki, Kim, Daeun, Sun, Shumin, Laurent, Thomas, Umeki, Miki, Ikeda, Saiko, Mochizuki, Satoshi, Oda, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209334/ https://www.ncbi.nlm.nih.gov/pubmed/30379940 http://dx.doi.org/10.1371/journal.pone.0206669 |
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