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Meniscal transplantation: procedures, outcomes, and rehabilitation

Meniscal allograft transplantation (MAT) is a possible treatment option for patients with joint pain after meniscectomy. It is necessary that the joint be aligned and stable. Current evidence shows that MAT improves pain and mechanical function in the mid to long term with patients reporting signifi...

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Autores principales: Young, James, Tudor, Francois, Mahmoud, Ahmed, Myers, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209369/
https://www.ncbi.nlm.nih.gov/pubmed/30774475
http://dx.doi.org/10.2147/ORR.S94378
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author Young, James
Tudor, Francois
Mahmoud, Ahmed
Myers, Peter
author_facet Young, James
Tudor, Francois
Mahmoud, Ahmed
Myers, Peter
author_sort Young, James
collection PubMed
description Meniscal allograft transplantation (MAT) is a possible treatment option for patients with joint pain after meniscectomy. It is necessary that the joint be aligned and stable. Current evidence shows that MAT improves pain and mechanical function in the mid to long term with patients reporting significantly improved outcomes at up to 15 years following surgery. Studies on survivorship showed up to 76% graft survival at 10 years. Recent studies have suggested a chondroprotective effect, but there is, at present, no evidence to support MAT in the prevention of osteoarthritis. This review article reported the current evidence for MAT showing support for fresh frozen, nonirradiated allografts. However, further research is required to determine the ideal indications for MAT, the optimal graft fixation method, and the safest rehabilitation protocol.
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spelling pubmed-62093692019-02-15 Meniscal transplantation: procedures, outcomes, and rehabilitation Young, James Tudor, Francois Mahmoud, Ahmed Myers, Peter Orthop Res Rev Review Meniscal allograft transplantation (MAT) is a possible treatment option for patients with joint pain after meniscectomy. It is necessary that the joint be aligned and stable. Current evidence shows that MAT improves pain and mechanical function in the mid to long term with patients reporting significantly improved outcomes at up to 15 years following surgery. Studies on survivorship showed up to 76% graft survival at 10 years. Recent studies have suggested a chondroprotective effect, but there is, at present, no evidence to support MAT in the prevention of osteoarthritis. This review article reported the current evidence for MAT showing support for fresh frozen, nonirradiated allografts. However, further research is required to determine the ideal indications for MAT, the optimal graft fixation method, and the safest rehabilitation protocol. Dove Medical Press 2017-05-15 /pmc/articles/PMC6209369/ /pubmed/30774475 http://dx.doi.org/10.2147/ORR.S94378 Text en © 2017 Young et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Young, James
Tudor, Francois
Mahmoud, Ahmed
Myers, Peter
Meniscal transplantation: procedures, outcomes, and rehabilitation
title Meniscal transplantation: procedures, outcomes, and rehabilitation
title_full Meniscal transplantation: procedures, outcomes, and rehabilitation
title_fullStr Meniscal transplantation: procedures, outcomes, and rehabilitation
title_full_unstemmed Meniscal transplantation: procedures, outcomes, and rehabilitation
title_short Meniscal transplantation: procedures, outcomes, and rehabilitation
title_sort meniscal transplantation: procedures, outcomes, and rehabilitation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209369/
https://www.ncbi.nlm.nih.gov/pubmed/30774475
http://dx.doi.org/10.2147/ORR.S94378
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