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Meniscal transplantation: procedures, outcomes, and rehabilitation
Meniscal allograft transplantation (MAT) is a possible treatment option for patients with joint pain after meniscectomy. It is necessary that the joint be aligned and stable. Current evidence shows that MAT improves pain and mechanical function in the mid to long term with patients reporting signifi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209369/ https://www.ncbi.nlm.nih.gov/pubmed/30774475 http://dx.doi.org/10.2147/ORR.S94378 |
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author | Young, James Tudor, Francois Mahmoud, Ahmed Myers, Peter |
author_facet | Young, James Tudor, Francois Mahmoud, Ahmed Myers, Peter |
author_sort | Young, James |
collection | PubMed |
description | Meniscal allograft transplantation (MAT) is a possible treatment option for patients with joint pain after meniscectomy. It is necessary that the joint be aligned and stable. Current evidence shows that MAT improves pain and mechanical function in the mid to long term with patients reporting significantly improved outcomes at up to 15 years following surgery. Studies on survivorship showed up to 76% graft survival at 10 years. Recent studies have suggested a chondroprotective effect, but there is, at present, no evidence to support MAT in the prevention of osteoarthritis. This review article reported the current evidence for MAT showing support for fresh frozen, nonirradiated allografts. However, further research is required to determine the ideal indications for MAT, the optimal graft fixation method, and the safest rehabilitation protocol. |
format | Online Article Text |
id | pubmed-6209369 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-62093692019-02-15 Meniscal transplantation: procedures, outcomes, and rehabilitation Young, James Tudor, Francois Mahmoud, Ahmed Myers, Peter Orthop Res Rev Review Meniscal allograft transplantation (MAT) is a possible treatment option for patients with joint pain after meniscectomy. It is necessary that the joint be aligned and stable. Current evidence shows that MAT improves pain and mechanical function in the mid to long term with patients reporting significantly improved outcomes at up to 15 years following surgery. Studies on survivorship showed up to 76% graft survival at 10 years. Recent studies have suggested a chondroprotective effect, but there is, at present, no evidence to support MAT in the prevention of osteoarthritis. This review article reported the current evidence for MAT showing support for fresh frozen, nonirradiated allografts. However, further research is required to determine the ideal indications for MAT, the optimal graft fixation method, and the safest rehabilitation protocol. Dove Medical Press 2017-05-15 /pmc/articles/PMC6209369/ /pubmed/30774475 http://dx.doi.org/10.2147/ORR.S94378 Text en © 2017 Young et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Young, James Tudor, Francois Mahmoud, Ahmed Myers, Peter Meniscal transplantation: procedures, outcomes, and rehabilitation |
title | Meniscal transplantation: procedures, outcomes, and rehabilitation |
title_full | Meniscal transplantation: procedures, outcomes, and rehabilitation |
title_fullStr | Meniscal transplantation: procedures, outcomes, and rehabilitation |
title_full_unstemmed | Meniscal transplantation: procedures, outcomes, and rehabilitation |
title_short | Meniscal transplantation: procedures, outcomes, and rehabilitation |
title_sort | meniscal transplantation: procedures, outcomes, and rehabilitation |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209369/ https://www.ncbi.nlm.nih.gov/pubmed/30774475 http://dx.doi.org/10.2147/ORR.S94378 |
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