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High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy
How appetite is modulated by physiological, contextual, or pharmacological influence is still unclear. Specifically, the discovery of appetite modulators is compromised by the abundance of side effects that usually limit in vivo drug action. We set out to identify neuroactive drugs that trigger only...
Autores principales: | Jordi, Josua, Guggiana-Nilo, Drago, Bolton, Andrew D, Prabha, Srishti, Ballotti, Kaitlyn, Herrera, Kristian, Rennekamp, Andrew J., Peterson, Randall T., Lutz, Thomas A., Engert, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209392/ https://www.ncbi.nlm.nih.gov/pubmed/30402545 http://dx.doi.org/10.1126/sciadv.aav1966 |
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