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High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy

How appetite is modulated by physiological, contextual, or pharmacological influence is still unclear. Specifically, the discovery of appetite modulators is compromised by the abundance of side effects that usually limit in vivo drug action. We set out to identify neuroactive drugs that trigger only...

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Detalles Bibliográficos
Autores principales: Jordi, Josua, Guggiana-Nilo, Drago, Bolton, Andrew D, Prabha, Srishti, Ballotti, Kaitlyn, Herrera, Kristian, Rennekamp, Andrew J., Peterson, Randall T., Lutz, Thomas A., Engert, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209392/
https://www.ncbi.nlm.nih.gov/pubmed/30402545
http://dx.doi.org/10.1126/sciadv.aav1966

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