Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis

The multiresistance of A. ruhlandii 155B, B. cenocepacia 122, and P. aeruginosa 48B strains isolated from patients with cystic fibrosis was established. The antibacterial effect of allicin, dimethyl thiosulfinate, and dipropyl thiosulfinate on multidrug-resistant strains was shown. Thiosulfinates ca...

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Autores principales: Kulikova, V. V., Chernukha, M. Yu., Morozova, E. A., Revtovich, S. V., Rodionov, A. N., Koval, V. S., Avetisyan, L. R., Kuliastova, D. G., Shaginyan, I. A., Demidkina, T. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209396/
https://www.ncbi.nlm.nih.gov/pubmed/30397530
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author Kulikova, V. V.
Chernukha, M. Yu.
Morozova, E. A.
Revtovich, S. V.
Rodionov, A. N.
Koval, V. S.
Avetisyan, L. R.
Kuliastova, D. G.
Shaginyan, I. A.
Demidkina, T. V.
author_facet Kulikova, V. V.
Chernukha, M. Yu.
Morozova, E. A.
Revtovich, S. V.
Rodionov, A. N.
Koval, V. S.
Avetisyan, L. R.
Kuliastova, D. G.
Shaginyan, I. A.
Demidkina, T. V.
author_sort Kulikova, V. V.
collection PubMed
description The multiresistance of A. ruhlandii 155B, B. cenocepacia 122, and P. aeruginosa 48B strains isolated from patients with cystic fibrosis was established. The antibacterial effect of allicin, dimethyl thiosulfinate, and dipropyl thiosulfinate on multidrug-resistant strains was shown. Thiosulfinates can have both bacteriostatic and bactericidal effects depending on the microorganism and the concentration. The studied thiosulfinates may be candidates for the development of alternative antibiotic drugs to treat infections caused by multidrug-resistant pathogens.
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spelling pubmed-62093962018-11-05 Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis Kulikova, V. V. Chernukha, M. Yu. Morozova, E. A. Revtovich, S. V. Rodionov, A. N. Koval, V. S. Avetisyan, L. R. Kuliastova, D. G. Shaginyan, I. A. Demidkina, T. V. Acta Naturae Research Article The multiresistance of A. ruhlandii 155B, B. cenocepacia 122, and P. aeruginosa 48B strains isolated from patients with cystic fibrosis was established. The antibacterial effect of allicin, dimethyl thiosulfinate, and dipropyl thiosulfinate on multidrug-resistant strains was shown. Thiosulfinates can have both bacteriostatic and bactericidal effects depending on the microorganism and the concentration. The studied thiosulfinates may be candidates for the development of alternative antibiotic drugs to treat infections caused by multidrug-resistant pathogens. A.I. Gordeyev 2018 /pmc/articles/PMC6209396/ /pubmed/30397530 Text en Copyright ® 2018 Park-media Ltd. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kulikova, V. V.
Chernukha, M. Yu.
Morozova, E. A.
Revtovich, S. V.
Rodionov, A. N.
Koval, V. S.
Avetisyan, L. R.
Kuliastova, D. G.
Shaginyan, I. A.
Demidkina, T. V.
Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis
title Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis
title_full Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis
title_fullStr Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis
title_full_unstemmed Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis
title_short Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis
title_sort antibacterial effect of thiosulfinates on multiresistant strains of bacteria isolated from patients with cystic fibrosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209396/
https://www.ncbi.nlm.nih.gov/pubmed/30397530
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